Clinical reference
The evidence behind every treatment
One reference page per treatment: what it does, what the studies show and what the risks are. Every claim links to an FDA label, a peer-reviewed study or a clinical guideline.
Prices and availability are listed in the catalog.
Hormones & menopause
Estradiol for Menopause: Evidence, the 2025 Label Change, and Safety
Estradiol for menopause: how the patch and gel work, what the WHI data and the 2025 FDA label change mean, side effect rates, and who should not use it.
Micronized Progesterone in HRT: Endometrial Protection and Safety
Micronized progesterone in hormone therapy: how it protects the uterus with estrogen, the evidence, the sleep effect, and who should not take it.
Oxybutynin for Hot Flashes: Evidence, Dosing, and Safety
Oxybutynin for menopausal hot flashes: how this bladder drug cuts hot flashes, the trial evidence, the dose, side effects, and the dementia question.
Paroxetine for Hot Flashes: Evidence, Dosing, and the Tamoxifen Caution
Low-dose paroxetine for menopausal hot flashes: how it works, the trial evidence, the 7.5 mg dose, side effects, and why to avoid it with tamoxifen.
Venlafaxine for Hot Flashes: Evidence, Dosing, and Safety
Venlafaxine for menopausal hot flashes: how this SNRI works, the trial evidence, off-label use, dosing, side effects, and who it suits.
Hair loss
Dutasteride for Hair Loss: Evidence, Off-Label Status, and Safety
Dutasteride for male pattern hair loss: how it lowers DHT more than finasteride, the evidence, its off-label US status, and real side effect rates.
Finasteride for Hair Loss: Clinical Evidence, Timeline, and Safety
Finasteride for male pattern hair loss: how it works, the trial evidence, the timeline to results, side effect rates, and how it compares to dutasteride.
Ketoconazole Shampoo for Hair Loss: Evidence and Safety
Ketoconazole shampoo as a hair-loss add-on: what the limited evidence shows, how it is used with finasteride and minoxidil, and the real safety picture.
Oral Minoxidil for Hair Loss: Evidence, Dosing, and Safety
Low-dose oral minoxidil for hair loss: how the pill works, what the studies show, the side effect rates, and how it compares to topical minoxidil.
Skin
Azelaic Acid for Rosacea and Acne: Evidence, Uses, and Safety
Azelaic acid for rosacea and acne: how the prescription gel and cream work, the trial evidence, side effects, and how it compares to other topicals.
Doxycycline for Acne and Rosacea: How It Works, Evidence, and Safety
Doxycycline for acne and rosacea: how the antibiotic and anti-inflammatory effects work, the trial evidence, side effects, and why courses are kept short.
Latanoprost for Eyelash Growth: Evidence, Off-Label Use, and Risks
Latanoprost is a glaucoma drop used off-label for eyelash growth: what the trials show, the iris pigmentation risk, and how it compares to Latisse.
Tretinoin for Acne and Wrinkles: Evidence, Timeline, and Safety
Tretinoin for acne and fine wrinkles: how the topical retinoid works, the trial evidence, the slow timeline, managing irritation, and pregnancy facts.
Migraine
Rizatriptan for Migraine: How It Works, Evidence, and Safety
Rizatriptan for acute migraine: how this fast triptan stops an attack, the evidence, the tablet versus the melt, side effects, and heart cautions.
Sumatriptan for Migraine: How It Works, Evidence, and Safety
Sumatriptan for acute migraine: how the first triptan stops an attack, the trial evidence, when to take it, side effects, and the heart-related cautions.